A COMMON BICYCLIC PROTEIN-KINASE CASCADE INACTIVATES THE REGULATORY ENZYMES OF FATTY-ACID AND CHOLESTEROL-BIOSYNTHESIS

被引：501

作者：

CARLING, D

ZAMMIT, VA

HARDIE, DG

机构：

[1] UNIV DUNDEE,DEPT BIOCHEM,MRC,PROT PHOSPHORYLAT GRP,DUNDEE DD1 4HN,SCOTLAND

[2] HANNAH RES INST,AYR KA6 5HL,SCOTLAND

来源：

FEBS LETTERS | 1987年 / 223卷 / 02期

关键词：

D O I：

10.1016/0014-5793(87)80292-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：217 / 222

页数：6

共 25 条

[1]

AREBALO RE, 1981, J BIOL CHEM, V256, P571

[2] CHARACTERIZATION AND REGULATION OF REDUCTASE KINASE, A PROTEIN-KINASE THAT MODULATES THE ENZYMIC ACTIVITY OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE [J].

BEG, ZH ;

STONIK, JA ;

BREWER, HB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (09) :4375-4379

[3]

BROWNSEY RW, 1987, ENZYMES B, V18, P123, DOI DOI 10.1016/S1874-6047(08)60256-5

[4] ISOLATION OF A CYCLIC-AMP-INDEPENDENT PROTEIN-KINASE FROM RAT-LIVER AND ITS EFFECT ON THE ENZYMATIC-ACTIVITY OF ACETYL-COA CARBOXYLASE [J].

CARLING, D ;

HARDIE, DG .

BIOCHEMICAL SOCIETY TRANSACTIONS, 1986, 14 (06) :1076-1077

[5] DIURNAL CHANGES IN THE FRACTION OF 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE IN THE ACTIVE FORM IN RAT-LIVER MICROSOMAL FRACTIONS [J].

EASOM, RA ;

ZAMMIT, VA .

BIOCHEMICAL JOURNAL, 1984, 220 (03) :739-745

[6]

EDWARDS PA, 1972, J LIPID RES, V13, P396

[7] REGULATION OF SYNTHESIS AND DEGRADATION OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE BY LOW-DENSITY LIPOPROTEIN AND 25-HYDROXYCHOLESTEROL IN UT-1 CELLS [J].

FAUST, JR ;

LUSKEY, KL ;

CHIN, DJ ;

GOLDSTEIN, JL ;

BROWN, MS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (17) :5205-5209

[8] PHOSPHORYLATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE BY MICROSOMAL 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE KINASE [J].

FERRER, A ;

HEGARDT, FG .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1984, 230 (01) :227-237

[9] ACTIVATION OF RAT-LIVER CYTOSOLIC 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE KINASE BY ADENOSINE 5'-MONOPHOSPHATE [J].

FERRER, A ;

CAELLES, C ;

MASSOT, N ;

HEGARDT, FG .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 132 (02) :497-504

[10] DIURNAL-VARIATIONS OF LIPOGENIC ENZYMES, THEIR SUBSTRATE AND EFFECTOR LEVELS, AND LIPOGENESIS FROM TRITIATED-WATER IN RAT-LIVER [J].

FUKUDA, H ;

KATSURADA, A ;

IRITANI, N .

BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 835 (02) :163-168

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