2-STEP BINDING OF EUKARYOTIC RIBOSOMES TO BROME MOSAIC-VIRUS RNA-3

被引：54

作者：

AHLQUIST, P ^{[1
]}

DASGUPTA, R ^{[1
]}

SHIH, DS ^{[1
]}

ZIMMERN, D ^{[1
]}

KAESBERG, P ^{[1
]}

机构：

[1] UNIV WISCONSIN,COLL AGR & LIFE SCI,DEPT BIOCHEM,MADISON,WI 53706

来源：

NATURE | 1979年 / 281卷 / 5729期

关键词：

D O I：

10.1038/281277a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Although brome mosaic virus RNA3 has only one translatable cistron, it can bind two 80S ribosomes at initiation. One ribosome binds at the first AUG codon (bases 92-94). The other binds nearer the 5' end at an entry or holding site. Disome formation is thus unrelated to a silent cistron ~1,000 bases downstream. © 1979 Nature Publishing Group.

引用

页码：277 / 282

页数：6

共 29 条

[1] AUG IS ONLY RECOGNIZABLE SIGNAL SEQUENCE IN 5' NON-CODING REGIONS OF EUKARYOTIC MESSENGER-RNA [J].

BARALLE, FE ;

BROWNLEE, GG .

NATURE, 1978, 274 (5666) :84-87

[2] EFFECT OF 5'-TERMINAL STRUCTURE AND BASE COMPOSITION ON POLYRIBONUCLEOTIDE BINDING TO RIBOSOMES [J].

BOTH, GW ;

FURUICHI, Y ;

MUTHUKRISHNAN, S ;

SHATKIN, AJ .

JOURNAL OF MOLECULAR BIOLOGY, 1976, 104 (03) :637-658

[3]

CHU LY, 1978, J BIOL CHEM, V253, P5228

[4] NUCLEOTIDE-SEQUENCE OF A VIRAL-RNA FRAGMENT THAT BINDS TO EUKARYOTIC RIBOSOMES [J].

DASGUPTA, R ;

SHIH, DS ;

SARIS, C ;

KAESBERG, P .

NATURE, 1975, 256 (5519) :624-628

[5] TRANSLATION OF VIRUS MESSENGER-RNA - SYNTHESIS OF BACTERIOPHAGE-Q-BETA PROTEINS IN A CELL-FREE EXTRACT FROM WHEAT EMBRYO [J].

DAVIES, JW ;

KAESBERG, P .

JOURNAL OF VIROLOGY, 1973, 12 (06) :1434-1441

[6] MAPPING ADENINES, GUANINES, AND PYRIMIDINES IN RNA [J].

DONISKELLER, H ;

MAXAM, AM ;

GILBERT, W .

NUCLEIC ACIDS RESEARCH, 1977, 4 (08) :2527-2537

[7] ROLE OF COMPLEXES BETWEEN 40-S RIBOSOMAL-SUBUNIT AND MET-TRANSFER-RNA-FMET IN INITIATION OF PROTEIN-SYNTHESIS IN WHEAT-GERM SYSTEM [J].

HUNTER, AR ;

JACKSON, RJ ;

HUNT, T .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 75 (01) :159-170

[8]

KNOWLAND J, 1975, INSERM (Institut National de la Sante et de la Recherche Medicale) Colloque, V47, P211

[9]

KOZAK M, 1978, J BIOL CHEM, V253, P6568

[10]

KOZAK M, 1977, J BIOL CHEM, V252, P6895

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