ENDOGENOUS OPIATES AND BEHAVIORAL-RESPONSES TO ENVIRONMENTAL NOVELTY

被引：65

作者：

KATZ, RJ

GELBART, J

机构：

[1] Mental Health Research Institute, Department of Psychiatry, University of Michigan Medical Center, Ann Arbor

来源：

BEHAVIORAL BIOLOGY | 1978年 / 24卷 / 03期

关键词：

D O I：

10.1016/S0091-6773(79)90197-4

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Endogenous opiates (endorphins) mediate a variety of motivational and behavioral states. We examined the possible contributions of endorphins to the exploratory behavior of mice. Naloxone, a blocker of opiate receptors, depressed hole board exploratory activity and entry into a novel environment. It also reduced responding for sensory stimulation. Finally, a direct correlation was demonstrated between exploratory behavior on the one hand, and enkephalin-induced behavioral activation on the other. © 1978 Academic Press Inc.

引用

页码：338 / 348

页数：11

共 28 条

[1]

AKIL H, 1977, PSYCHOPHARMACOLOGY T, P292

[2] ANALGESIA INDUCED INVIVO BY CENTRAL ADMINISTRATION OF ENKEPHALIN IN RAT [J].