ABNORMALITIES OF MAGNETIC-RESONANCE-IMAGING OF THE CENTRAL-NERVOUS-SYSTEM IN PATIENTS WITH SYSTEMIC LUPUS-ERYTHEMATOSUS CORRELATE WITH DISEASE SEVERITY

被引：20

作者：

CAULI, A ^{[1
]}

MONTALDO, C ^{[1
]}

PELTZ, MT ^{[1
]}

NURCHIS, P ^{[1
]}

SANNA, G ^{[1
]}

GARAU, P ^{[1
]}

PALA, R ^{[1
]}

PASSIU, G ^{[1
]}

MATHIEU, A ^{[1
]}

机构：

[1] UNIV CAGLIARI,DEPT CLIN MED,I-09100 CAGLIARI,ITALY

来源：

CLINICAL RHEUMATOLOGY | 1994年 / 13卷 / 04期

关键词：

SYSTEMIC LUPUS ERYTHEMATOSUS; MAGNETIC RESONANCE IMAGING; CENTRAL NERVOUS SYSTEM;

D O I：

10.1007/BF02243004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Forty randomly selected patients with systemic lupus erythematosus (SLE) were studied by clinical and serologic parameters and magnetic resonance imaging (MRI). Abnormal MRI was found in 15/40 patients (37,5%): all 15 cases showed multiple widespread small-sized areas of increased signal in T2 in the white matter; in one of these patients MRI also displayed a large area with a reduced signal in T1 and an increased signal in T2 involving both the white and the gray matter. Among the 15 patients with abnormal MRI, only 7 had neuropsychiatric symptoms. The presence of MRI changes was highest in patients with organic type symptoms and was associated to the highest disease severity scores. A long-term follow up of asymptomatic patients would be useful to establish whether the application of MRI is appropriate for the assessment of CNS involvement in SLE.

引用

页码：615 / 618

页数：4

共 18 条

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