MONACOLIN-K, A NEW HYPOCHOLESTEROLEMIC AGENT THAT SPECIFICALLY INHIBITS 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE

被引：198

作者：

ENDO, A

机构：

来源：

JOURNAL OF ANTIBIOTICS | 1980年 / 33卷 / 03期

关键词：

D O I：

10.7164/antibiotics.33.334

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：334 / 336

页数：3

共 11 条

[1] COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY [J].

ENDO, A ;

KURODA, M ;

TANZAWA, K .

FEBS LETTERS, 1976, 72 (02) :323-326

[2] MONACOLIN-K, A NEW HYPOCHOLESTEROLEMIC AGENT PRODUCED BY A MONASCUS SPECIES [J].

ENDO, A .

JOURNAL OF ANTIBIOTICS, 1979, 32 (08) :852-854

[3] ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM [J].

ENDO, A ;

KURODA, M ;

TSUJITA, Y .

JOURNAL OF ANTIBIOTICS, 1976, 29 (12) :1346-1348

[4]

ENDO A, 1979, BIOCHIM BIOPHYS ACTA, V575, P266

[5] SOLUBILIZATION AND PARTIAL-PURIFICATION OF HEPATIC 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE [J].

HELLER, RA ;

GOULD, RG .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1973, 50 (03) :859-865

[6] MECHANISM FOR ELEVATION OF HEPATIC CHOLESTEROL-SYNTHESIS AND SERUM-CHOLESTEROL LEVELS IN TRITON WR-1339-INDUCED HYPERLIPIDEMIA [J].

KURODA, M ;

TANZAWA, K ;

TSUJITA, Y ;

ENDO, A .

BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 489 (01) :119-125

[7]

KURODA M, 1977, BIOCHIM BIOPHYS ACTA, V486, P70

[8] HYPOLIPIDEMIC EFFECTS IN MONKEYS OF ML-236B, A COMPETITIVE INHIBITOR OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE [J].

KURODA, M ;

TSUJITA, Y ;

TANZAWA, K ;

ENDO, A .

LIPIDS, 1979, 14 (06) :585-589

[9]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[10] HYPOLIPIDEMIC EFFECTS IN DOGS OF ML-236B, A COMPETITIVE INHIBITOR OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE [J].

TSUJITA, Y ;

KURODA, M ;

TANZAWA, K ;

KITANO, N ;

ENDO, A .

ATHEROSCLEROSIS, 1979, 32 (03) :307-313

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