EFFECT OF 6-ALPHA SUBSTITUTION IN PENICILLINS AND 7-ALPHA SUBSTITUTION IN CEPHALOSPORINS UPON BETA-LACTAM REACTIVITY

被引：29

作者：

INDELICA.JM ^{[1
]}

WILHAM, WL ^{[1
]}

机构：

[1] ELI LILLY & CO,LILLY RES LABS,INDIANAPOLIS,IN 46206

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1974年 / 17卷 / 05期

关键词：

D O I：

10.1021/jm00251a012

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：528 / 529

页数：2

共 9 条

[1] 6-ALKYL PENICILLINS AND 7-ALKYL CEPHALOSPORINS [J].

BOHME, EHW ;

APPLEGAT.HE ;

EWING, JB ;

FUNKE, PT ;

PUAR, MS ;

DOLFINI, JE .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (02) :230-236

[2] ALKALINE DEGRADATION PRODUCT OF CEPHRADINE [J].

COHEN, AI ;

FUNKE, PT ;

PUAR, MS .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1973, 62 (09) :1559-1561

[3] BIOCHEMICAL AND MICROBIOLOGICAL STUDIES ON 7-METHOXYCEPHALOSPORINS [J].

HO, PPK ;

TOWNER, RD ;

INDELICATO, JM ;

WILHAM, WJ ;

SPITZER, WA ;

KOPPEL, GA .

JOURNAL OF ANTIBIOTICS, 1973, 26 (05) :313-314

[4] BIOCHEMICAL AND MICROBIOLOGICAL STUDIES ON 6-SUBSTITUTED PENICILLINS [J].

HO, PPK ;

TOWNER, RD ;

SPITZER, WA ;

KOPPEL, GA ;

INDELICATO, JM .

JOURNAL OF ANTIBIOTICS, 1972, 25 (10) :627-+

[5]

HOLLEY RW, 1951, J AM CHEM SOC, V73, P3172

[6] SUBSTITUENT EFFECTS UPON BASE HYDROLYSIS OF PENICILLINS AND CEPHALOSPORINS - COMPETITIVE INTRAMOLECULAR NUCLEOPHILIC AMINO ATTACK IN CEPHALOSPORINS [J].

INDELICA.JM ;

NORVILAS, TT ;

PFEIFFER, RR ;

WHEELER, WJ ;

WILHAM, WL .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (05) :523-527

[7] BETA-LACTAM ANTIBIOTICS FROM STREPTOMYCES [J].

NAGARAJAN, R ;

BOECK, LD ;

GORMAN, M ;

HAMILL, RL ;

HIGGENS, CE ;

HOEHN, MM ;

STARK, WM ;

WHITNEY, JG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (09) :2308-+

[8]

TIPPER DJ, 1968, J BIOL CHEM, V243, P3169

[9] RELATIVE SUBSTITUENT EFFECTS ON ALKALINE SOLVOLYSIS OF BETA-LACTAMS (2-AZETIDINONES) AND AMIDES [J].

WASHKUHN, RJ ;

ROBINSON, JR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1971, 60 (08) :1168-&

← 1 →