SELECTIVE ACETAMINOPHEN METABOLITE BINDING TO HEPATIC AND EXTRAHEPATIC PROTEINS - AN INVIVO AND INVITRO ANALYSIS

被引：68

作者：

BARTOLONE, JB

BEIERSCHMITT, WP

BIRGE, RB

HART, SGE

WYAND, S

COHEN, SD

KHAIRALLAH, EA

机构：

[1] UNIV CONNECTICUT,DEPT MOLEC & CELL BIOL,U-125,75 N EAGLEVILLE RD,STORRS,CT 06268

[2] UNIV CONNECTICUT,DEPT PHARMACOL & TOXICOL,STORRS,CT 06268

[3] UNIV CONNECTICUT,DEPT PATHOBIOL,STORRS,CT 06268

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1989年 / 99卷 / 02期

关键词：

D O I：

10.1016/0041-008X(89)90006-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：240 / 249

页数：10

共 27 条

[1] IMMUNOCHEMICAL DETECTION OF ACETAMINOPHEN-BOUND LIVER PROTEINS [J].

BARTOLONE, JB ;

SPARKS, K ;

COHEN, SD ;

KHAIRALLAH, EA .

BIOCHEMICAL PHARMACOLOGY, 1987, 36 (08) :1193-1196

[2] IMMUNOCHEMICAL ANALYSIS OF ACETAMINOPHEN COVALENT BINDING TO PROTEINS - PARTIAL CHARACTERIZATION OF THE MAJOR ACETAMINOPHEN-BINDING LIVER PROTEINS [J].

BARTOLONE, JB ;

BIRGE, RB ;

SPARKS, K ;

COHEN, SD ;

KHAIRALLAH, EA .

BIOCHEMICAL PHARMACOLOGY, 1988, 37 (24) :4763-4774

[3]

BEND JR, 1974, HDB PHYSL REACT ENV, V26, P419

[4] ACETAMINOPHEN-INDUCED HEPATIC NECROSIS AND RENAL FAILURE [J].

BOYER, TD ;

ROUFF, SL .

JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1971, 218 (03) :440-&

[5] EFFECT OF PIPERONYL BUTOXIDE POST-TREATMENT ON ACETAMINOPHEN HEPATOTOXICITY [J].

BRADY, JT ;

MONTELIUS, DA ;

BEIERSCHMITT, WP ;

WYAND, DS ;

KHAIRALLAH, EA ;

COHEN, SD .

BIOCHEMICAL PHARMACOLOGY, 1988, 37 (10) :2097-2099

[6] INSITU FORMATION OF THE ACETAMINOPHEN METABOLITE COVALENTLY BOUND IN KIDNEY AND LUNG SUPPORTIVE EVIDENCE PROVIDED BY TOTAL HEPATECTOMY [J].

BREEN, K ;

WANDSCHEER, JC ;

PEIGNOUX, M ;

PESSAYRE, D .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (01) :115-116

[7]

BROWN JR, 1976, FED PROC, V35, P2141

[8] QUANTITATIVE-DETERMINATION OF GLUTATHIONE, CYSTEINE, AND N-ACETYL CYSTEINE CONJUGATES OF ACETAMINOPHEN BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY [J].

BUCKPITT, AR ;

ROLLINS, DE ;

NELSON, SD ;

FRANKLIN, RB ;

MITCHELL, JR .

ANALYTICAL BIOCHEMISTRY, 1977, 83 (01) :168-177

[9] N-ACETYL-PARA-BENZOQUINONE IMINE - A CYTOCHROME-P-450-MEDIATED OXIDATION-PRODUCT OF ACETAMINOPHEN [J].

DAHLIN, DC ;

MIWA, GT ;

LU, AYH ;

NELSON, SD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (05) :1327-1331

[10] SPECIES-DIFFERENCES IN HEPATIC GLUTATHIONE DEPLETION, COVALENT BINDING AND HEPATIC NECROSIS AFTER ACETAMINOPHEN [J].

DAVIS, DC ;

POTTER, WZ ;

JOLLOW, DJ ;

MITCHELL, JR .

LIFE SCIENCES, 1974, 14 (11) :2099-2109

← 1 2 3 →