PROGESTERONE SYNTHESIS IN PURE TROPHOBLASTS OF HUMAN CHORIOCARCINOMA

被引：19

作者：

HUANG, WY

PATTILLO, RA

DELFS, E

MATTINGLY, RF

机构：

[1] Department of Gynecology and Obstetrics, Marquette School of Medicine, Milwaukee County General Hospital, Milwaukee, WI

来源：

STEROIDS | 1969年 / 14卷 / 06期

关键词：

D O I：

10.1016/S0039-128X(69)80081-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A pure trophoblastic cell line of human choriocarcinoma has been successfully grown in tissue culture. Such a biological system provides an ideal model for the study of cellular metabolism in vitro. Cultures of this pure cell line were incubated with pregnenolone-7H3 in the Waymouth's medium (MB 752-1), which contained no serum or exogenous enzyme. Based on the biochemical data and radiochemical purity criteria, the result demonstrated that the trophoblast of human choriocarcinoma synthesized progesterone in vitro. © 1969.

引用

页码：755 / +

页数：1

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