LACK OF NEURAL CONTROL AND REACTIVITY TO VASOACTIVE AGENTS IN MALIGNANT GLIOMA ARTERIES

被引：6

作者：

HARDEBO, JE

KAHRSTROM, J

SALFORD, LG

机构：

[1] UNIV LUND HOSP,DEPT NEUROSURG,S-22185 LUND,SWEDEN

[2] UNIV LUND HOSP,DEPT MED CELL RES,S-22185 LUND,SWEDEN

来源：

JOURNAL OF NEUROSURGERY | 1991年 / 74卷 / 04期

关键词：

BRAIN TUMOR; GLIOMA; VASOREACTIVITY; VASCULAR NERVE;

D O I：

10.3171/jns.1991.74.4.0633

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Vessels in malignant brain tumors have a defective blood-brain barrier. It is important to know if tumor vessels respond to vasoactive agents, since systemic administration of vasodilatory agents together with chemotherapy could increase the access of these drugs to the tumor. It was found that arteries in human malignant gliomas have no neural control and are totally nonreactive to various vasoactive agents. The vessels lose their reactivity within 1 to 2 mm outside the visible tumor front.

引用

页码：633 / 635

页数：3

共 11 条

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[3]

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