RENAL INULIN CLEARANCE VERSUS TOTAL PLASMA CLEARANCE OF 51CR-EDTA

被引:223
作者
BROCHNER.J
GIESE, J
ROSSING, N
机构
[1] Department of Clinical Physiology, Glostrup Hospital, Copenhagen
关键词
Cr-EDTA; Glomerular filtration rate; Inulin; Kidneys; Plasma volume; Radioisotopes; Renal clearance; Total plasma clearance; Tracer kinetics;
D O I
10.3109/00365516909081695
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Simultaneous measurements of inulin clearance by infusion and clearance from of 51Cr-EDTA after single injection were performed in 17 subjects. 51Cr-EDTA-clearance was calculated as the ratio between plasma volume and the area under the plasma curve from t = o to infinity. Urine collection is not needed. Whole-body counting showed 4.5% retention after 72 hours. The use of 51Cr-EDTA clearance for deteermination of GFR is justisfied in view of the close correspondence between inulin clearance and plasma clearance of 51Cr-EDTA. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:301 / &
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