THE COGNITIVE PARADIGM AND THE IMMUNOLOGICAL HOMUNCULUS

被引：321

作者：

COHEN, IR

机构：

[1] Irun R. Cohen is at the Dept of Cell Biology, The Weizmann Institute of Science, Rehovot

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 12期

关键词：

D O I：

10.1016/0167-5699(92)90024-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In last month's issue of Immunology Today, Irun Cohen discussed the inadequacies of the clonal selection paradigm and proposed a cognitive paradigm in which preformed internal images guide and restrict the process of clonal activation. Here he clarifies the nature of these internal images, drawing on concrete examples from the image of infection and the image of self, the immunological homunculus.

引用

页码：490 / 494

页数：5

共 42 条

[1]

BENNUN A, 1982, J IMMUNOL, V128, P1450

[2] VACCINATION AGAINST AUTOIMMUNE ENCEPHALOMYELITIS WITH LYMPHOCYTE-T LINE CELLS REACTIVE AGAINST MYELIN BASIC-PROTEIN [J].