EFFLUX RATE OF NOREPINEPHRINE FROM PLATELETS AND ITS RELATION TO BLOOD-PRESSURE

被引：41

作者：

MATTIASSON, I ^{[1
]}

MATTIASSON, B ^{[1
]}

HOOD, B ^{[1
]}

机构：

[1] UNIV LUND, CTR CHEM, S-22101 LUND, SWEDEN

来源：

LIFE SCIENCES | 1979年 / 24卷 / 24期

关键词：

SULPHOMUCOPOLYSACCHARIDE-PROTEIN COMPLEX; 5-HYDROXYTRYPTAMINE ORGANELLES; ACCUMULATION; STORAGE; PLASMA; MODEL; HYPERTENSION; DEBRISOQUIN; METABOLISM; DOPAMINE;

D O I：

10.1016/0024-3205(79)90103-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The uptake and efflux rate of norepinephrine in platelets were studied in 48 men and 15 women. Of these, 40 had a diastolic blood pressure .gtoreq. 95 mm Hg. If the initial efflux rate, k, was correlated to the diastolic blood pressure a highly significant relationship (r [correlation coefficient] = 0.748, P < 0.001) was obtained, i.e., a high diastolic blood pressure is correlated to a rapid efflux of norepinephrine from platelets. No correlation occurred between uptake values and diastolic blood pressure.

引用

页码：2265 / 2272

页数：8

共 35 条

[1] SULPHOMUCOPOLYSACCHARIDE-PROTEIN COMPLEX IN ADRENERGIC VESICLE (GRANULE) FRACTION FROM NERVES AND TISSUE [J].