SIGNAL-TRANSDUCTION BY BETA-CATENIN

被引：355

作者：

GUMBINER, BM

机构：

[1] Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021

来源：

CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 05期

关键词：

D O I：

10.1016/0955-0674(95)80104-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus. The adenomatous polyposis coli tumor suppressor protein is also implicated in beta-catenin signaling.

引用

收藏

页码：634 / 640

页数：7

相关论文

共 51 条

[1]

ABERLE H, 1994, J CELL SCI, V107, P3655

[2] PATHWAYS OF CELL COMMUNICATION DURING DEVELOPMENT - SIGNALING AND EPISTASES [J].

ARIAS, AM .

TRENDS IN GENETICS, 1994, 10 (07) :219-222

[3] LOSS OF EPITHELIAL DIFFERENTIATION AND GAIN OF INVASIVENESS CORRELATES WITH TYROSINE PHOSPHORYLATION OF THE E-CADHERIN BETA-CATENIN COMPLEX IN CELLS TRANSFORMED WITH A TEMPERATURE-SENSITIVE V-SRC GENE [J].

BEHRENS, J ;

VAKAET, L ;

FRIIS, R ;

WINTERHAGER, E ;

VANROY, F ;

MAREEL, MM ;

BIRCHMEIER, W .

JOURNAL OF CELL BIOLOGY, 1993, 120 (03) :757-766

[4] CADHERIN EXPRESSION IN CARCINOMAS - ROLE IN THE FORMATION OF CELL-JUNCTIONS AND THE PREVENTION OF INVASIVENESS [J].

BIRCHMEIER, W ;

BEHRENS, J .

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1994, 1198 (01) :11-26

[5] EXPRESSION OF WNT-1 IN PC12 CELLS RESULTS IN MODULATION OF PLAKOGLOBIN AND E-CADHERIN AND INCREASED CELLULAR ADHESION [J].

BRADLEY, RS ;

COWIN, P ;

BROWN, AMC .

JOURNAL OF CELL BIOLOGY, 1993, 123 (06) :1857-1865

[6] PLAKOGLOBIN AND BETA-CATENIN - DISTINCT BUT CLOSELY RELATED [J].

BUTZ, S ;

STAPPERT, J ;

WEISSIG, H ;

KEMLER, R .

SCIENCE, 1992, 257 (5073) :1142-1144

[7] PLAKOGLOBIN - A PROTEIN COMMON TO DIFFERENT KINDS OF INTERCELLULAR ADHERING JUNCTIONS [J].

COWIN, P ;

KAPPRELL, HP ;

FRANKE, WW ;

TAMKUN, J ;

HYNES, RO .

CELL, 1986, 46 (07) :1063-1073

[8]

DAWID IB, 1994, J BIOL CHEM, V269, P6259

[9]

FAGOTTO F, 1994, DEVELOPMENT, V120, P3667

[10] EMBRYONIC AXIS INDUCTION BY THE ARMADILLO REPEAT DOMAIN OF BETA-CATENIN - EVIDENCE FOR INTRACELLULAR SIGNALING [J].

FUNAYAMA, N ;

FAGOTTO, F ;

MCCREA, P ;

GUMBINER, BM .

JOURNAL OF CELL BIOLOGY, 1995, 128 (05) :959-968

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