MODIFIED RNA-POLYMERASE TRANSCRIBES A CLONED GENE UNDER SPORULATION CONTROL IN BACILLUS-SUBTILIS

被引：119

作者：

HALDENWANG, WG

LOSICK, R

机构：

[1] Biological Laboratories, Harvard University, Cambridge

来源：

NATURE | 1979年 / 282卷 / 5736期

关键词：

D O I：

10.1038/282256a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A modified form of RNA polymerase from B. subtilis selectively transcribes a cloned gene under early sporulation control. This RNA polymerase lacks .sigma. factor but contains a newly identified subunit of MW 37,000, termed P37. P37 could be a regulatory protein that partly controls an early stage of spore development.

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页码：256 / 260

页数：5

相关论文

共 18 条

[1] A MEMBRANE-FILTER TECHNIQUE FOR DETECTION OF COMPLEMENTARY DNA [J].

DENHARDT, DT .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1966, 23 (05) :641-&

[2]

DOI RH, 1977, ANNU REV GENET, V11, P29, DOI 10.1146/annurev.ge.11.120177.000333

[3] GEL ELECTROPHORETIC SEPARATION OF COMPLEMENTARY STRANDS OF BACTERIOPHAGE DNA [J].

HAYWARD, GS .

VIROLOGY, 1972, 49 (01) :342-&

[4]

HOCH JA, 1976, ADV GENET, V18, P67

[5] CHANGE IN TEMPLATE SPECIFICITY OF RNA POLYMERASE DURING SPORULATION OF BACILLUS SUBTILIS [J].

LOSICK, R ;

SONENSHEIN, AL .

NATURE, 1969, 224 (5214) :35-+

[6] SPECIFICITY OF SUBSTRATE RECOGNITION BY ECORI RESTRICTION ENDONUCLEASE [J].

POLISKY, B ;

GREENE, P ;

GARFIN, DE ;

MCCARTHY, BJ ;

GOODMAN, HM ;

BOYER, HW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (09) :3310-3314

[7] LABELING DEOXYRIBONUCLEIC-ACID TO HIGH SPECIFIC ACTIVITY INVITRO BY NICK TRANSLATION WITH DNA-POLYMERASE I [J].

RIGBY, PWJ ;

DIECKMANN, M ;

RHODES, C ;

BERG, P .

JOURNAL OF MOLECULAR BIOLOGY, 1977, 113 (01) :237-251

[8] CATABOLIC REPRESSION OF BACTERIAL SPORULATION [J].

SCHAEFFER, P ;

MILLET, J ;

AUBERT, JP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 54 (03) :704-+

[9] CHLORAMPHENICOL RESTORES SIGMA FACTOR ACTIVITY TO SPORULATING BACILLUS-SUBTILIS [J].

SEGALL, J ;

TJIAN, R ;

PERO, J ;

LOSICK, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (12) :4860-4863

[10] CLONED BACILLUS-SUBTILIS DNA CONTAINING A GENE THAT IS ACTIVATED EARLY DURING SPORULATION [J].

SEGALL, J ;

LOSICK, R .

CELL, 1977, 11 (04) :751-761