SPECIFIC ANOSMIA TO 1-PYRROLINE: THE SPERMOUS PRIMARY ODOR

被引:56
作者
Amoore, John E. [1 ]
Forrester, L. Janet [1 ]
Buttery, Ron G. [1 ]
机构
[1] USDA, Western Reg Res Lab Agr Res Serv, Berkeley, CA 94710 USA
关键词
odor thresholds; primary odor; l-pyrroline; Schiff's base; semen; specific anosmia; spermous'' odor;
D O I
10.1007/BF00988831
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
About 20% of human subjects are specifically anosmic to the Odor of the heterocyclic Schiff's base 1-pyrroline Odor threshold measurements on 33 nitrogenous bases were made with panels of specific anosmics and normal observers. The anosmia proved to be very selective, and was encountered only with 1-pyrroline and its homolog 1-piperideine. The odor of 1-pyrroline resembles very closely that of human semen, and possibly represents a vestigial pheromone. It is suggested that this specific anosmia corresponds with the absence of a new olfactory primary, the "spermous" odor. The same odor occurs as an impurity in several organic reagents and can be detected in a variety of biological materials.
引用
收藏
页码:299 / 310
页数:12
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