LACK OF ABNORMALITY IN BRAIN AROMATIC AMINES IN RATS AND MICE SUSCEPTIBLE TO AUDIOGENIC SEIZURE

The levels of certain amines (catecholamines, 5‐HT, and ‘histamine’) and of certain enzymes (tyrosine hydroxylase, tryptophan hydroxylase, ChAc, or AChE) in whole brain or selected brain areas of rats and mice susceptible to audiogenic seizure have been compared with the levels in matched groups of non‐sensitive animals. Sensitive groups included both those where susceptibility is inborn and those where it is induced by administration of methionine sulphoximine or thiosemicarbazide. No significant difference was found which could be correlated with susceptibility to audiogenic seizure. Copyright © 1969, Wiley Blackwell. All rights reserved