INTRACEREBROVENTRICULAR ANGIOTENSIN II-INDUCED THIRST AND SODIUM APPETITE IN RAT ARE BLOCKED BY THE AT1 RECEPTOR ANTAGONIST, LOSARTAN (DUP-753), BUT NOT BY THE AT(2) ANTAGONIST, CGP-42112B

被引：81

作者：

BERESFORD, MJ ^{[1
]}

FITZSIMONS, JT ^{[1
]}

机构：

[1] PHYSIOL LAB,CAMBRIDGE CB2 3EG,ENGLAND

来源：

EXPERIMENTAL PHYSIOLOGY | 1992年 / 77卷 / 05期

关键词：

D O I：

10.1113/expphysiol.1992.sp003643

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

In the rat, intakes of water and 1.8 % NaCl induced by I.C.V. angiotensin II were inhibited by prior I.C.V. injection of the angiotensin subtype 1 receptor antagonist, Losartan, but not by the subtype 2 receptor antagonist, CGP 42112B. Drinking induced by i.c.v. carbachol was unaffected by either antagonist.

引用

收藏

页码：761 / 764

页数：4

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