MAJOR HISTOCOMPATIBILITY COMPLEX OF THE MOUSE

被引：464

作者：

KLEIN, J

机构：

[1] Max-Planck-Institut für Biologie, Abteilung Immungenetik

来源：

SCIENCE | 1979年 / 203卷 / 4380期

关键词：

D O I：

10.1126/science.104386

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Like physicists striving to develop a unified field theory, immunologists are attempting to bring order to the microcosmos of defense reactions. Indications are that one of the most important constants in this microcosmos is the major histocompatibility complex (MHC) of the species. A test of any interpretation of the MHC's role in immunity is how well it explains this system's polymorphism. One of the most crucial questions an MHC hypothesis must answer is: Why are there so many alleles at this complex? Copyright © 1979 AAAS.

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页码：516 / 521

页数：6

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