SOMATOSTATIN INHIBITS RELEASE OF THYROTROPIN RELEASING FACTOR FROM ORGAN-CULTURES OF RAT HYPOTHALAMUS

被引：97

作者：

HIROOKA, Y

HOLLANDER, CS

SUZUKI, S

FERDINAND, P

JUAN, SI

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 09期

关键词：

D O I：

10.1073/pnas.75.9.4509

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Somatostatin in concentrations of 10-6 to 10-8 M inhibited basal release of thyrotoprin releasing factor in organ culture of rat hypothalamus. Norepinephrine in doses of 10-4-10-6 M induced released of thyrotropin releasing factor which increased progressively with time and was temperature and dose dependent. This enhanced thyrotropin-releasing-factor release was inhibited by somatostatin at 10-6-10-8 M.

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页码：4509 / 4513

页数：5

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