CHROMATIN-MEDIATED TRANSCRIPTIONAL REPRESSION IN YEAST

被引：89

作者：

ROTH, SY

机构：

[1] Department of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Houston

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0959-437X(95)80004-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and alpha 2.

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页码：168 / 173

页数：6

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